Current Issue : July - September Volume : 2013 Issue Number : 3 Articles : 7 Articles
Hyperlipidemia and obesity are one of the major health problems faced in the developing and developed countries. Many plants possess antihyperlipidemic activity and many of them are mentioned in traditional literature, but the specific mechanism and the compound responsible for such activity still remain obscure. MGAT is one of the key enzymes responsible for the synthesis of triglyceride. Anhtocephalus indicus is one of the many plant which is mentioned in traditional literature for the treatment of obesity. The methanolic extract of the plant showed significant inhibition of MGAT enzyme with an IC50 value of 0.00085 μg/ml. Bioactivity guided fractionation of the methanolic extract was carried out to isolate the active compound or fraction responsible for the activity....
The Trikatu churna (Piper nigrum, Piper longum, Zingiber officinale) and lab scale churna preparation (Piper nigrum, Zingiber officinale and Eugenia caryophyllus) was evaluated for Appetizer activity. The Trikatu churna and lab scale preparation was screened for phytochemical studies and also tested for appetizer activity. The phytochemical screening of Trikatu churna showed the presence of alkaloids, flavonoids, tannins, lignins and steroids and lab scale churna preparation also showed presence of alkaloids, flavonoids, tannins, lignins and steroids. Trikatu churna exhibited appetizer activity, but the highest activity was noticed in laboratory churna preparation, this might be due to the multifunctional effect of all the three plant ingredients of laboratory preparation. Based on the above results, it is confirmed that, combination of Piper nigrum, Zingiber officinale and Eugenia caryophyllus in laboratory churna offered batter appetizer effect than using the Trikatu churna....
Plants are the primary source of raw materials for plant based medicine since ancient times. The traditional herbal medicines are receiving great importance in the health care sector. In Indian system of medicine i.e, ayurveda, one of the plant Cuminum cyminum belonging to family Apiaceae is a grassy plant with 15-50 cm height, growing in many parts of world. In folk medicine, the fruits of this plant have been used to treat diarrhea, toothache and epilepsy. In recent years, there are some reports regarding the anti-diabetic, estrogenic activities, anticonvulsant, antioxidant, antibacterial, and anti aggregatory activity of the fruit essential oil of Cuminum cyminum. The present review on Cuminum cyminum is to know its importance with respect to pharmacognosy and pharmacology in detail....
Herbal drugs have been used since ancient times as medicines for the treatment of a range of diseases. In spite of the great advances observed in modern medicine in recent decades, plants still make an important contribution to health care. Anorexia is become the most serious GIT disorder which characterized by loss of appetite or decreased appetite despite basic caloric needs. A number of synthetic appetizers are available in practice however their effectiveness is associated with side effect, dose related chronic toxicity and there is no patient compliance. While herbal medicines are widely accepted throughout the globe because of their higher therapeutic efficacy along with least side effects. They are also useful in treating loss of appetite in elderly persons those suffering from reduced production of stomach acid digestive enzymes and removes toxins from digestive system. Treatment which is mostly used in Indian food is ginger, coriander, fennel, long piper, capsicum and black piper etc. Due to deficiency of these it has turned towards the scientific research with respect to the herbal appetizer. Appetite-suppressants are those drugs which promote weight loss by decreasing appetite or increasing the sensation of fullness, resultant decreased food consumption and they are effective because they help reduce the uncomfortable feeling of hunger. These medications promote weight loss by helping to diminish appetite or by increasing the subjective feeling of fullness. The most popular natural appetite suppressants are green tea extract hoodia and ephedra....
A new, simple, sensitive, precise and robust high-performance thin layer chromatographic (HPTLC) method was developed for the estimation of Tribulosin and (Mono ammonium glycyrrhizinate) MAG in herbal extracts and polyherbal formulation. Analysis of Tribulosin and MAG were performed on TLC aluminium pre-coated plates with silica gel 60F-254 as stationary phase. Linear ascending development was carried out in twin trough glass chamber saturated with mobile phase consisting of butanol: GAA: water (6: 1: 3, v/v/v) for Tribulosin and chloroform: methanol: GAA: water: formic acid (1.8: 0.4: 0.8: 0.2: 0.1, v/v/v/v/v) for MAG at room temperature (25±2°C). After development the plate was derivatized with vanillin-sulphuric acid (H2SO4) for both Tribulosin and MAG. Camag TLC scanner III was used for spectrodensitometric scanning and analysis of plate in absorbance mode at 454 and 254 nm for Tribulosin and MAG respectively. The system was found to give compact spots for Tribulosin (Rf 0.41) and MAG (Rf 0.56). The data for calibration plots showed good linear relationship with r2=0.9994 and r2=0.9992 in the concentration range of 75–450 ng and 40-240 ng for Tribulosin and MAG respectively. According to international conference on harmonization (ICH) guidelines the present method was validated for precision, repeatability and recovery. The limits of detection and quantification were determined. Statistical analysis of the data showed that the method is reproducible and selective for estimation of Tribulosin and MAG....
A number of herbs belonging to the genus Jatropha are renowned for their medicinal benefits. The successive extracts of roots of three Jatropha species viz. Jatropha curcas, Jatropha gossypifolia and Jatropha integerrima were tested for their antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Micrococcus luteus and Escherichia coli and antifungal activity against Aspegillus niger and Candida albicans using cup plate method and minimum inhibitory concentration (MIC). The extracts were found to hold significant antimicrobial activity with MIC ranging from 0.78 to 12.5 mg/ml of extract....
Today synthetic indicators are the choice of acid-base titrations but due to environmental pollution, availability and cost, the search for natural compounds as an acid-base indicator was started. Indicators help to determine the equivalence point in acid–base titrations (neutralization titrations). They show sharp color change with respect to change in pH; commonly used indicator for neutralization titrations is synthetic in nature. The highly colored pigments obtained from plants are found to exhibit color changes with variation of pH. The chemical substances which possess an apparent change in color of analyte and titrant reacting mixture very close to the point in the ongoing titration known as indicator. Acid-base indicators are the substances which changes color with changes in pH. They are usually weak acids and bases and also known as neutralization indicator. Today various plants extracts are used as acid base indicator such as Rosa sinensis, Dahlia pinnata and Butea monosperma etc. These indicators are economically and easily available. In this review importance of pH indicators in analytical chemistry along with the use of plant material or the extracts obtained from plant is described....
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